2-Methyl-1,8-naphthyridine-3-carboxylic acid

2-Methyl-1,8-naphthyridine-3-carboxylic acid - Names and Identifiers

Name	2-methyl-1,8-naphthyridine-3-carboxylic acid
Synonyms	[1,8]naphthyridine-3-carboxyL 2-methyl-1,8-naphthyridine-3-carboxylic acid 2-Methyl-1,8-naphthyridine-3-carboxylic acid 1,8-Naphthyridine-3-carboxylic acid, 2-methyl- 1,8-naphthyridine-3-carboxylic acid, 2-methyl- 1,8-Naphthyridine-3-carboxylicacid,2-methyl-(9CI) 4-hydroxy-2-Methyl-1,8-naphthyridine-3-carboxylic acid 2-Methyl-1,8-Naphthyridine-3-Carboxylic Acid Monohydrate 2-METHYL-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID MONOHYDRATE 3-Carboxy-2-methyl-1,8-naphthyridine, 1,8-Diaza-2-methylnaphthalene-3-carboxylic acid
CAS	387350-60-9
InChI	InChI=1/C10H8N2O2/c1-6-8(10(13)14)5-7-3-2-4-11-9(7)12-6/h2-5H,1H3,(H,13,14)

2-Methyl-1,8-naphthyridine-3-carboxylic acid - Physico-chemical Properties

Molecular Formula	C10H8N2O2
Molar Mass	188.18
Density	1.355
Melting Point	191-195
Boling Point	356℃
Flash Point	169℃
Vapor Presure	1.08E-05mmHg at 25°C
pKa	1.33±0.30(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.673

2-Methyl-1,8-naphthyridine-3-carboxylic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Note	Irritant

2-Methyl-1,8-naphthyridine-3-carboxylic acid - Introduction

2-methyl-1, acid is an organic compound with the chemical formula C12H9NO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White crystalline solid
-Melting point: 147-150°C
-Solubility: Insoluble in water, slightly soluble in common organic solvents such as ethanol and dimethylformamide

Use:
2-methyl-1, acid has some uses in the pharmaceutical and pesticide fields, such:
-As an antifungal drug intermediate: can be used to synthesize a class of antifungal drugs
-for the synthesis of antibiotic intermediates: can be used for the synthesis of antibiotic drugs
-Used in the synthesis of organic photosensitizers: can be used as a part of photocompounds in photochemical reactions

Preparation Method:
2-methyl-1, the preparation method of acid can be carried out by the following steps:
1.2-methyl -1,8-naphthyridine and sodium hydroxide are reacted in ethanol to generate 2-methyl -1,8-naphthyridine alcohol.
2. acidify 2-methyl-1,8-naphthyridine alcohol with acid to generate 2-methyl-1, acid.

Safety Information:

Last Update：2024-04-09 02:00:45